Muse Dash is a vertical-scrolling rhythm game where players tap and hold on the screen to the beat of energetic music. Two characters automatically run forward while players control their attacks to hit airborne enemies and avoid ground-based obstacles. Each successful hit contributes to the player's score and combo multiplier.

The mobile version features touchscreen controls optimized for handheld play, with the entire screen divided into two main tap zones. Gameplay is fast-paced, requiring precise timing across numerous songs and difficulty levels. The experience is enhanced by vibrant anime-style visuals that sync with the music.