Gangster City: Mafia Crime is a third-person action game set in a large open-world metropolis. Players complete missions and engage in combat to rise through the ranks of organized crime. The touchscreen controls handle movement, driving, and shooting against rival gangs and law enforcement.

The gameplay loop involves undertaking story-driven jobs, from street-level crimes to more complex heists, to earn money and respect. Players can freely explore the city, acquire new weapons and vehicles, and manage their criminal empire. Progression is tied to expanding influence and unlocking stronger equipment.